Nexgard Combo לחתולים 5.5-16.5 פאונד (2.5-7.5 ק"ג) - 3 חבילות
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Common brand names

Single ingredient

  • Activyl Topical Solution for Dogs and Cats

Combined ingredients

No generic products are available.

Uses of Indoxacarb

Indoxacarb is a broad-spectrum insecticide used to control fleas in dogsוcats. It is also indicated for the control of flea allergy dermatitis.

Method of application

External application, supplied as a topical/spot-on solution.

Dosage and administration

Indoxacarb is available in both canine and feline formulas, with the dosage based on the animal’s body weight. Ensure that you weigh your pet and only use the product on the species for which it is intended.

Topical solutions should be administered as indicated by the instructions on the product package. This will provide maximum efficacy and will help to ensure the product is applied in a position where the animal cannot lick it off.

A single dose of Indoxacarb will kill existing fleas within 24 hours and will provide residual protection against adult and immature fleas for at least four weeks. Indoxacarb should not be administered more than once per month.

Indoxacarb remains effective on dogs even after shampooing or swimming, but dogs should not be allowed to swim or be treated with shampoo for 48 hours after treatment. The water fastness of Indoxacarb on cats has not been established.

Possible side effects

Transient skin irritation, hair loss or hair clumping may occur at the site of application.

Animals that lick the application site immediately after treatment may experience increased salivation. This is not a sign of intoxication and should disappear within several minutes.

Adverse reactions in animals treated with Indoxacarb may include squinting, head shaking, salivation, and scratching or rubbing the site of application or the face.

Additional reported side effects in cats licking the product include gastrointestinal and neurological signs.


Indoxacarb is for external use only and should not be administered orally.

Do not use on dogs under 8 weeks of age or weighing less than 4 pounds (1.8 kg).

Do not use on cats under 8 weeks of age or weighing less than 2 pounds (0.9 kg)

Do not use with pregnant or lactating animals or with animals intended for breeding.

Do not allow animals to groom each other following treatment.

Signs of toxicity

Indoxacarb toxicity is rare but may cause symptoms such as weakness, depression, drooling or abnormal gait.

If you suspect your pet has had an overdose, please contact your veterinarian immediately.


Protect from moisture. Store at room temperature away from foodstuffs.


This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. This page may not include all side effects, uses, brand names or applications.


Indoxacarb drug information sheet
Indoxacarb Information Sheet

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